Which two factors influence an animal's disposition?

The correct answer highlights that both genetic make-up and environmental situation play critical roles in determining an animal's disposition. Genetic make-up refers to the inherent traits and behaviors that are passed down from parents to offspring. These genetic factors can predispose an animal to certain temperaments, such as being more aggressive or more docile.

On the other hand, the environmental situation encompasses all external factors that an animal is exposed to during its life, which can influence behavior, stress levels, and overall temperament. This can include social interactions, training, handling by humans, and the animal's living conditions. For example, an animal raised in a calm, nurturing environment may develop a more stable and friendly disposition compared to one exposed to stress or neglect.

The combination of these two factors—genetic predispositions and the environmental context—ultimately shapes the disposition of an animal, making this choice the most comprehensive of the options provided.